Salvation, Iowa

Salvation, Iowa is where John Winchester and his boys get the latest lead on the Yellow-Eyed demon. John calls Missouri Mosley to confirm the lead, and when she does, the boys take the trip to Salvation. While there, John gets the call that his friend, Jim Murphy had been killed, also killed while in Salvation, was Caleb, another of John's friends. He agrees to meet Meg to trade the gun in order for her to stop killing his family and friends. The boys don't want to split up, but John reminds them that they have a job to do: To find and kill Azazel before he kills another family that was in Sam psychic visions. It was in Salvation that Dean was in his fatal car accident and where he eventually ended up dying while in a coma.